Thessaly in the Ottoman period, organized in communities, manages to safeguard its cultural heritage. The religious expression of the Christians is presented through the murals from Polidendri in Agia and also through the church icons from Larissa and from Asproklisia in Kalambaka, among which two two-sided icons from Krania of Olympus stand out.
The Ottoman and Jewish presence stands out on the equivalent tomb pillars, while two column capitals from the Mosque of Chasan Bei in Larissa are exhibited, typical of the Ottoman craftsmanship. The financial prosperity of Ampelakia, due to the red knitting thread trade, are represented through the murals of the mansions, while coin treasures signify the circulation of a variety of coinage throughout Thessaly.